Publications

Phase I Publications

Since September 2022, the Center for ChemoEnzymatic Synthesis has led to the following publications:

Total Center Publications

Photobiocatalytic Enantioselective C(sp3)–H Acylation Enabled by Thiamine-dependent Enzymes via Intermolecular Hydrogen Atom Transfer

Lu, Y.-C.; Adukure, R.; Roy, S.; Chien, D.; McGill, M.; Scheidt, K. A.; Fasan, R. Photobiocatalytic Enantioselective C(sp3)–H Acylation Enabled by Thiamine-dependent Enzymes via Intermolecular Hydrogen Atom Transfer. ChemRxiv,...

Generation of connections between protein sequence space and chemical space to enable a predictive model for biocatalysis

Paton, A.; Boiko, D.; Perkins, J.; Cemalovic, N; Reschützegger, T.; Gomes, G.; Narayan, A.* ChemRxiv 10.26434/chemrxiv-2024-w4dtr.

Autonomous chemical research with large language models

Boiko, A. D.; MacKnight, R.; Kline, B.; Gomes, G.* Nature 2023, 624, 570-578.

Enabling Broader Adoption of Biocatalysis in Organic Chemistry

Romero, E. O.; Saucedo, A. T.; Hernández-Meléndez, J. R.; Yang, D.; Chakrabarty, S.; Narayan, A. R. H.* JACS Au 2023, 3, 2073-2085.